We also analysed the numbers of deaths caused by CKD and the age-standardised death rates (ASDRs) by time period, region, age, risk factors and sex.ĭata analysed in the present study were obtained from the online database the Global Health Data Exchange (GHDx) query tool ( ), which were based on literature studies, survey data, surveillance data, medical records, health insurance claims and statistical model analysis. Considering these factors, we carried out research on the global CKD-related death burden and related risk factors from 1990 to 2019. However, the details of CKD-related mortality have been poorly studied worldwide. In the context of current global Big Data, deep quantitative analyses of CKD morbidity and mortality and their influencing factors are crucial in guiding decisions by policymakers and healthcare providers. 8 9 Although several studies on CKD have been conducted, 1 10 detailed death burden analyses of recent three-decade period are scarce and need to be further studied. 4–7 Complex influencing factors make the diagnosis and treatment of CKD difficult, which seriously increases the public health burden. Studies have found that the sociodemographic index (SDI), human development level, economic situation, and health access and quality index are closely related to the CKD incidence. 1 Once diagnosed with CKD, the kidney function would gradually decline until the end-stage renal disease or even death, with little chance of reversal, imposing a heavy economic burden on society. 3 The incidence rate increased by 29.3% compared with that in 1990. 1 The prevalence of CKD has increased with the ageing of the population and has become a global public health problem. 1 2 According to relevant statistics, there were an estimated 697.5 million cases of CKD worldwide in 2017. Chronic kidney disease (CKD) refers to chronic renal dysfunction caused by various factors for more than 3 months.
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